The aim of the project is to develop a cheap and simple cellular model for the Shwachman-Diamond Syndrome by the use of the well-known HL-60 cell line. The syndrome is a rare autosomal recessive disease. The HL-60 cell line is easy to manipulate and maintaine in culture. Lead institution University of Insubria – Department of Medicine and Surgery Institution National Research Council – Institute for Genetic and Biomedical Research (IT) ReferenceM.E.S. HL-60Project locations Italy
