RHOMOLO is the European Commission's spatial computable general equilibrium model. It is developed and maintained by the TEDAM team at JRC Seville in collaboration with DG REGIO. It is used for policy impact assessment and provides sectoral, regional and time specific results based on scenario analysis.
RHOMOLO covers all NUTS 2 regions of the EU and disaggregates their economies into ten NACE Rev. 2 sectors. You can access the publicly available RHOMOLO data, and the latest technical description of the model. The latest journal articles and working papers on RHOMOLO results can be found here.
In short, the model agents make optimising decisions, and spatial interactions between regions are captured through trade flows and factor mobility. This makes RHOMOLO well suited for simulating the effects of policies targeting human capital, transport infrastructure, and R&D and innovation.