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Biopersistence of nanomaterials used in food-related applications: in vitro tests to assess dissolution and biological fate

The aim of the project is the validation and standardisation of an in vitro dissolution tests for nanoparticles in the agri-food sector. The test should enable the physicochemical characterization of the particles after the digestion process and lysosomal processing. If nanoparticles persist as such after gastrointestinal digestion, for example, they might be absorbed in the gut and a nano-specific risk assessment is required.

Lead institution

Istituto Superiore di Sanità - National Institute of Health