The JRC contributed to the development of a low cost and highly efficient screening strategy to implement the European Commission's Recommendation for a definition of nanomaterials.
A variety of EU regulations (Cosmetic Products, Novel Foods, Biocidal Products and the proposal for Medical Devices) require information on nanomaterials and an assessment of their safety. Essentially, according to the Commission's recommendation, a nanomaterial is a material containing particles and where more than half of the particles have at least one external dimension in the size range 1 nm – 100 nm.
To find out whether a material actually is a nanomaterial, and whether specific regulatory provisions apply, it is important to measure the size of particles from 1 nm up to several hundred nanometres. This can be costly and time-consuming since it often involves Transmission Electron Microscopy (TEM) and elaborate sample preparation.
It is also possible to identify nanomaterials by determining their volume specific surface area (VSSA). This involves the adsorption of a monolayer of an inert gas on the surface of the particles and can be done by a well-known, low cost and standardized method to be applied to dry powders without further sample preparation. This makes the approach very interesting.
However, there were many doubts whether the two methods TEM and VSSA always lead to the same classification. Therefore the EU FP7 project NanoDefine, in which the JRC leads the development of a decision-making framework for classification of nanomaterials as well as validation and standardization activities, evaluated the extent of agreement between the classifications obtained by using EM and VSSA on a large set of diverse particulate substances.
Based on the results obtained on highly characterised benchmark materials, the researchers derived an efficient strategy for distinguishing between nano- and non-nano materials. The strategy recommended by the NanoDefine consortium, which relies on the use of VSSA as screening method, is highly resource-efficient and cost-saving, and it should be included in a technical guidance for implementation of the nanomaterial definition.
Read more in: W. Wohlleben et al. "Reliable nanomaterial classification of powders using the volume-specific surface area method", J. Nanopart. Res. 19 (2017) 61, doi:10.1007/s11051-017-3741-x
Reliable nanomaterial classification of powders using the volume-specific surface area method
N. Gibson, H. Rauscher, G. Roebben, Comments on the article by A.J. Lecloux (J Nanopart Res (2015) 17:447) regarding the use of volume-specific surface area (VSSA) to classify nanomaterials, J. Nanopart. Res. 18 (2016) 250
Commission recommendation of 18 October 2011 on the definition of nanomaterial (2011/696/EU), 2011, Off. J. Eur. Union
Towards a review of the EC Recommendation for a revision of the term "nanomaterial" – Part 3 Scientific-technical evaluation of options to clarify the definition and to facilitate its implementation
Towards a Review of the EC recommendation for a definition of the term "nanomaterial" – Part 2: Assessment of information concerning the experience with the definition
Towards a Review of the EC recommendation for a definition of the term "nanomaterial" – Part 1 Compilation of information concerning the experience with the definition
- Publication date
- 30 March 2017